NARF antibody (Middle Region)
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- Target See all NARF Antibodies
- NARF (Nuclear Prelamin A Recognition Factor (NARF))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NARF antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Purified
- Immunogen
- NARF antibody was raised in rabbit using the middle region of NARF as the immunogen
- Top Product
- Discover our top product NARF Primary Antibody
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- Application Notes
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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NARF Blocking Peptide, catalog no. 33R-7931, is also available for use as a blocking control in assays to test for specificity of this NARF antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- NARF (Nuclear Prelamin A Recognition Factor (NARF))
- Alternative Name
- NARF (NARF Products)
- Synonyms
- NARF antibody, IOP2 antibody, 4430402O11Rik antibody, RGD1310894 antibody, wu:fa03c01 antibody, zgc:92186 antibody, nuclear prelamin A recognition factor antibody, nuclear prelamin A recognition factor L homeolog antibody, NARF antibody, NAEGRDRAFT_78871 antibody, VDBG_04882 antibody, Tsp_07547 antibody, Tsp_07549 antibody, Narf antibody, narf antibody, narf.L antibody
- Background
- Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. NARF binds to the prenylated prelamin A carboxyl-terminal tail domain. Synonyms: Polyclonal NARF antibody, Anti-NARF antibody, nuclear prelamin A recognition factor antibody, DKFZp434G0420 antibody, FLJ10067 antibody, IOP2 antibody.
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