CSTB antibody (N-Term)

Catalog No. ABIN929151

This anti-CSTB antibody is a Rabbit Polyclonal antibody detecting CSTB in WB. Suitable for Human.

Quick Overview for CSTB antibody (N-Term) (ABIN929151)

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSTB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CSTB Antibody

Binding Specificity: N-Term

Purification: Purified

Immunogen: CSTB antibody was raised in rabbit using the N terminal of CSTB as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CSTB Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CSTB antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for CSTB

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Alternative Name: CSTB

Background: CSTB is a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in CSTB gene are responsible for the primary defects in patients with progressive myoclonic epilepsy a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy. Synonyms: Polyclonal CSTB antibody, Anti-CSTB antibody, cystatin B, stefin B antibody, CST6 antibody, EPM1 antibody, PME antibody, STFB antibody.

Pathways: Response to Water Deprivation