UFD1L
Reactivity: Human
WB, IP
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB: 0.2-1 µg/mL Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Format
Lyophilized
Concentration
Lot specific
Buffer
Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice
Avoid repeated freeze/thaw cycles.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
Target
UFD1L
(Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
Alternative Name
UFD1L
Background
The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. Synonyms: Polyclonal UFD1L antibody, Anti-UFD1L antibody, ubiquitin fusion degradation 1 like, yeast antibody, UFD1 antibody.