BBS2 antibody (Middle Region)

Catalog No. ABIN929334

Product Details anti-BBS2 Antibody

Target: BBS2 (Bardet-Biedl Syndrome 2 (BBS2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BBS2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: BBS2 antibody was raised in rabbit using the middle region of BBS2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

BBS2 Blocking Peptide, catalog no. 33R-7948, is also available for use as a blocking control in assays to test for specificity of this BBS2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for BBS2

Target: BBS2 (Bardet-Biedl Syndrome 2 (BBS2))

Alternative Name: BBS2 (BBS2 Products)

Synonyms: fb80a05 antibody, wu:fb80a05 antibody, DKFZp468B105 antibody, DKFZp469L0919 antibody, BBS antibody, 2410125H22Rik antibody, AI447581 antibody, Bardet-Biedl syndrome 2 antibody, bardet-biedl syndrome 2 antibody, Bardet-Biedl syndrome 2 (human) antibody, bbs2 antibody, BBS2 antibody, Bbs2 antibody

Background: This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with six other BBS proteins. Synonyms: Polyclonal BBS2 antibody, Anti-BBS2 antibody, Bardet-Biedl syndrome 2 antibody, BBS antibody, MGC20703 antibody.

Pathways: Hedgehog Signaling