BTBD12 antibody (N-Term)

Catalog No. ABIN929369

The Rabbit Polyclonal anti-BTBD12 antibody has been validated for WB. It is suitable to detect BTBD12 in samples from Human.

Quick Overview for BTBD12 antibody (N-Term) (ABIN929369)

Target: BTBD12 (BTB (POZ) Domain Containing 12 (BTBD12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTBD12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BTBD12 Antibody

Binding Specificity: N-Term

Purification: Purified

Immunogen: BTBD12 antibody was raised in rabbit using the N terminal of BTBD12 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

BTBD12 Blocking Peptide, (ABIN5612371), is also available for use as a blocking control in assays to test for specificity of this BTBD12 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for BTBD12

Target: BTBD12 (BTB (POZ) Domain Containing 12 (BTBD12))

Alternative Name: BTBD12

Background: This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases. Synonyms: Polyclonal BTBD12 antibody, Anti-BTBD12 antibody, BTB, POZ domain containing 12 antibody, KIAA1784 antibody, KIAA1987 antibody, MUS312 antibody, SLX4 antibody.

Pathways: DNA Damage Repair