Cadherin 5 antibody (Middle Region)

Catalog No. ABIN929441

The Rabbit Polyclonal anti-Cadherin 5 antibody is suitable to detect Cadherin 5 in samples from Human. It has been validated for WB.

Quick Overview for Cadherin 5 antibody (Middle Region) (ABIN929441)

Target: Cadherin 5 (CDH5)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cadherin 5 Antibody

Binding Specificity: Middle Region

Purification: Purified

Immunogen: CDH5 antibody was raised in rabbit using the middle region of CDH5 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

CDH5 Blocking Peptide, (ABIN5612784), is also available for use as a blocking control in assays to test for specificity of this CDH5 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Cadherin 5

Target: Cadherin 5 (CDH5)

Alternative Name: CDH5

Background: This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Synonyms: Polyclonal CDH5 antibody, Anti-CDH5 antibody, cadherin 5, type 2, vascular endothelium antibody, 7B4 antibody, CD144 antibody, FLJ17376 antibody.

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2