Cytokeratin 18 antibody

Catalog No. ABIN930818

The Mouse Monoclonal anti-Cytokeratin 18 antibody has been validated for WB, IHC and ELISA. It is suitable to detect Cytokeratin 18 in samples from Cow.

Quick Overview for Cytokeratin 18 antibody (ABIN930818)

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reactivity: Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cytokeratin 18 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: Ks18-27

Product Details anti-Cytokeratin 18 Antibody

Purification: Protein G affinity chromatography

Immunogen: Keratin K18 antibody was raised in mouse using Cytoskeletal preparation from tumor cell line MCF-7 as the immunogen.

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in distilled water, final solution contains 0.09 % sodium azide, 0.5 % BSA in PBS buffer, pH 7.4

Concentration: Lot specific

Buffer: Supplied in lyophilized form.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for Cytokeratin 18

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Alternative Name: Keratin K18

Background: Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. Synonyms: Monoclonal Keratin K18 antibody, Anti Keratin K18 antibody, Cytokeratin 18 antibody.

Pathways: Apoptosis, Caspase Cascade in Apoptosis