ACIN1 antibody

Catalog No. ABIN930986

The Mouse Monoclonal anti-ACIN1 antibody has been validated for WB, ICC and DB. It is suitable to detect ACIN1 in samples from Human.

Quick Overview for ACIN1 antibody (ABIN930986)

Target: ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ACIN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Dot Blot (DB)

Clone: 2005C3a

Product Details anti-ACIN1 Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: ACIN1 antibody was raised in mouse using recombinant Human Apoptotic Chromatin Condensation Inducer 1 (Acin1)

Isotype: IgG1

Application Details

Application Notes: WB: 0.2-2 µg/mL, ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: ACIN1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for ACIN1

Target: ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))

Alternative Name: ACIN1

Background: ACIN1 is a component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3. Synonyms: Monoclonal ACIN1 antibody, Anti-ACIN1 antibody, Apoptotic chromatin condensation inducer 1 antibody, ACN antibody, ACINUS antibody, KIAA0670 antibody, DKFZp667N107 antibody.