MYCN antibody

Catalog No. ABIN930998

The Mouse Monoclonal anti-MYCN antibody is suitable to detect MYCN in samples from Human. It has been validated for DB.

Quick Overview for MYCN antibody (ABIN930998)

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MYCN antibody is un-conjugated

Application: Dot Blot (DB)

Clone: 986C1a

Product Details anti-MYCN Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: MYCN antibody was raised in mouse using recombinant Human V-Myc Myelocytomatosis Viral Related Oncogene, Neuroblastoma Derived (Avian)

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: MYCN antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for MYCN

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Alternative Name: MYCN

Background: This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Synonyms: Monoclonal MYCN antibody, Anti-MYCN antibody, V myc myelocytomatosis viral related oncogene neuroblastoma derived antibody, ODED antibody, MODED antibody, N-myc antibody.