CRSP-2 antibody

Catalog No. ABIN931010

The Mouse Monoclonal anti-CRSP-2 antibody has been validated for DB. It is suitable to detect CRSP-2 in samples from Human.

Quick Overview for CRSP-2 antibody (ABIN931010)

Target: CRSP-2 (Calcitonin Receptor-Stimulating Peptide-2 (CRSP-2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Application: Dot Blot (DB)

Clone: 2214C1a

Product Details anti-CRSP-2 Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: CRSP2 antibody was raised in mouse using recombinant Human Cofactor Required For Sp1 Transcriptional Activation, Subunit 2, 150 Kda (Crsp2)

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: CRSP2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for CRSP-2

Target: CRSP-2 (Calcitonin Receptor-Stimulating Peptide-2 (CRSP-2))

Alternative Name: CRSP2

Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. Synonyms: Monoclonal CRSP2 antibody, Anti-CRSP2 antibody, Cofactor required for Sp1 transcriptional activation subunit 2 antibody, CSRP antibody, RGR1 antibody, EXLM1 antibody, MED14 antibody, CXorf4 antibody, CRSP150 antibody, DRIP150 antibody, TRAP170 antibody, MGC104513 antibody.