AXUD1 antibody

Catalog No. ABIN931016

The Mouse Monoclonal anti-AXUD1 antibody has been validated for DB. It is suitable to detect AXUD1 in samples from Human.

Quick Overview for AXUD1 antibody (ABIN931016)

Target: AXUD1 (CSRNP1) (Cysteine-serine-Rich Nuclear Protein 1 (CSRNP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AXUD1 antibody is un-conjugated

Application: Dot Blot (DB)

Clone: 2055E3a

Product Details anti-AXUD1 Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: AXUD1 antibody was raised in mouse using recombinant Human Axin1 Up-Regulated 1 (Axud1)

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: AXUD1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for AXUD1

Target: AXUD1 (CSRNP1) (Cysteine-serine-Rich Nuclear Protein 1 (CSRNP1))

Alternative Name: AXUD1

Background: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene. Synonyms: Monoclonal AXUD1 antibody, Anti-AXUD1 antibody, AXIN1 up regulated 1 antibody, URAX1 antibody, TAIP-3 antibody, DKFZp566F164 antibody, FAM130B antibody.

Pathways: Platelet-derived growth Factor Receptor Signaling