HAND2 antibody

Catalog No. ABIN931183

This Mouse Monoclonal antibody specifically detects HAND2 in DB. It exhibits reactivity toward Human.

Quick Overview for HAND2 antibody (ABIN931183)

Target: HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HAND2 antibody is un-conjugated

Application: Dot Blot (DB)

Clone: HAND2C1a

Product Details anti-HAND2 Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: HAND2 antibody was raised in mouse using recombinant Human Heart And Neural Crest Derivatives Expressed 2 (Hand2)

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Mouse monoclonal anti-humanHAND2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for HAND2

Target: HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))

Alternative Name: HAND2

Background: The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development. Synonyms: Monoclonal HAND2 antibody, Anti-HAND2 antibody, Heart and neural crest derivatives expressed protein 2 antibody, Hed antibody, dHand antibody, DHAND2 antibody, Thing2 antibody, FLJ16260 antibody, MGC125303 antibody, MGC125304 antibody.

Pathways: Tube Formation, Feeding Behaviour