Estrogen Receptor alpha antibody (Estrogen Receptor 1) (AA 130-339)

Details for Product anti-ESR1 Antibody No. ABIN931399
Target
Binding Specificity
AA 130-339
43
31
29
27
26
24
23
21
21
18
17
16
16
16
15
15
15
13
11
11
10
8
7
6
5
5
5
5
4
4
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
594
255
206
40
33
12
10
9
7
7
5
5
4
3
3
1
1
Host
Mouse
453
177
2
1
1
Clonality (Clone)
Monoclonal ()
Conjugate
This Estrogen Receptor alpha antibody is un-conjugated
42
24
24
17
16
13
12
12
12
12
12
11
6
6
6
6
6
4
4
4
4
4
4
4
4
4
4
4
4
4
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
446
212
207
143
103
80
79
55
55
18
16
16
13
13
11
9
7
3
2
1
1
1
1
1
1
1
1
1
1
1
Options
Immunogen Estrogen Receptor antibody was raised in Mouse using a purified recombinant fragment of Estrogen Receptor(aa130-339) expressed in E. coli as the immunogen.
Clone 8H9A10
Isotype IgG1
Target
Alternative Name Estrogen Receptor (ESR1 Antibody Abstract)
Background Estrogen receptor refers to a group of receptors that are activated by the hormone estrogen. Two types of estrogen receptor exist: ER, which is a member of the nuclear hormone family of intracellular receptors, and the estrogen G protein-coupled receptor GPR30 (GPER), which is a G protein-coupled receptor. The main function of the estrogen receptor is as a DNA-binding transcription factor that regulates gene expression. However, the estrogen receptor has additional functions independent of DNA binding. Synonyms: Monoclonal Estrogen Receptor 1 antibody, Anti-Estrogen Receptor 1 antibody, DKFZp686N23123 antibody, ER antibody, ESR antibody, ESRA antibody, Era antibody, NR3A1 antibody, ESR1 antibody.
Pathways Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Application Notes ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
Storage RT/-20 °C
Storage Comment Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Images
Image no. 1 for anti-Estrogen Receptor 1 (ESR1) (AA 130-339) antibody (ABIN931399) Western Blot showing ESR1 antibody used against truncated Trx-ESR1 recombinant protei...