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Estrogen Receptor alpha antibody (AA 246-273)

ESR1 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3030871
  • Target See all Estrogen Receptor alpha (ESR1) Antibodies
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Binding Specificity
    • 32
    • 30
    • 26
    • 23
    • 21
    • 21
    • 21
    • 16
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 14
    • 12
    • 12
    • 10
    • 10
    • 10
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    AA 246-273
    Reactivity
    • 487
    • 173
    • 169
    • 19
    • 18
    • 10
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 398
    • 98
    • 2
    • 1
    Rabbit
    Clonality
    • 377
    • 124
    Polyclonal
    Conjugate
    • 223
    • 35
    • 24
    • 22
    • 19
    • 15
    • 15
    • 15
    • 15
    • 15
    • 15
    • 11
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    This Estrogen Receptor alpha antibody is un-conjugated
    Application
    • 294
    • 162
    • 142
    • 120
    • 98
    • 94
    • 80
    • 67
    • 40
    • 39
    • 24
    • 15
    • 10
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    Cross-Reactivity (Details)
    Expected species reactivity: Mouse, Rat, Bovine, Pig
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 246-273 from the human protein (alpha) was used as the immunogen for this Estrogen Receptor antibody.
    Isotype
    Ig Fraction
  • Application Notes
    The stated application concentrations are suggested starting amounts. Titration of the Estrogen Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at 4°C for up to one month. For long term, aliquot the Estrogen Receptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Alternative Name
    Estrogen Receptor (ESR1 Products)
    Synonyms
    LOC398734 antibody, AA420328 antibody, AU041214 antibody, ER-alpha antibody, ER[a] antibody, ERa antibody, ERalpha antibody, ESR antibody, Estr antibody, Estra antibody, Nr3a1 antibody, NR3A1 antibody, eralpha antibody, zfER[a] antibody, ER antibody, ESRA antibody, ESTRR antibody, Era antibody, akap12 antibody, cb27 antibody, esr1 antibody, fb72g12 antibody, id:ibd1202 antibody, sb:cb27 antibody, si:ch73-192g21.1 antibody, wu:fb72g12 antibody, wu:fc21c03 antibody, Esr antibody, RNESTROR antibody, ERALPHA antibody, er antibody, esr antibody, nr3a1 antibody, XER antibody, era antibody, esra antibody, ERbeta antibody, xesr-1 antibody, xlERalpha1 antibody, xlERalpha2 antibody, ESR1 antibody, estrogen receptor 1 L homeolog antibody, estrogen receptor 1 (alpha) antibody, estrogen receptor 1 antibody, A kinase (PRKA) anchor protein 12b antibody, esr1.L antibody, Esr1 antibody, ESR1 antibody, esr1 antibody, akap12b antibody
    Background
    This gene encodes an Estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. ERs are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
    UniProt
    P03372
    Pathways
    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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