CNOT2 antibody

Catalog No. ABIN932185

This Mouse Monoclonal antibody specifically detects CNOT2 in DB. It exhibits reactivity toward Human.

Quick Overview for CNOT2 antibody (ABIN932185)

Target: CNOT2 (CCR4-NOT Transcription Complex, Subunit 2 (CNOT2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CNOT2 antibody is un-conjugated

Application: Dot Blot (DB)

Clone: 2191C2a

Product Details anti-CNOT2 Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: CNOT2 antibody was raised in mouse using recombinant Human Ccr4-Not Transcription Complex, Subunit 2 (Cnot2)

Isotype: IgG2a

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: CNOT2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for CNOT2

Target: CNOT2 (CCR4-NOT Transcription Complex, Subunit 2 (CNOT2))

Alternative Name: CNOT2

Background: This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. Synonyms: Monoclonal CNOT2 antibody, Anti-CNOT2 antibody, CCR4-NOT transcription complex subunit 2 antibody, NOT2 antibody, CDC36 antibody, NOT2H antibody, HSPC131 antibody.

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance