KDM4A antibody

Catalog No. ABIN932195

The Mouse Monoclonal anti-KDM4A antibody has been validated for DB and ICC. It is suitable to detect KDM4A in samples from Human.

Quick Overview for KDM4A antibody (ABIN932195)

Target: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KDM4A antibody is un-conjugated

Application: Dot Blot (DB), Immunocytochemistry (ICC)

Clone: 3559D5a

Product Details anti-KDM4A Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: JMJD2 A antibody was raised in mouse using recombinant Omo Sapiens Jumonji Domain Containing 2

Isotype: IgG2a

Application Details

Application Notes: ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: JMJD2 A antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for KDM4A

Target: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Alternative Name: JMJD2A

Background: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylationspecific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. Synonyms: Monoclonal JMJD2A antibody, Anti-JMJD2A antibody, Jumonji domain-containing protein 2A antibody, KIAA0677 antibody, JHDM3A antibody.

Pathways: Warburg Effect