Reticulon 3 antibody

Catalog No. ABIN932228

The Mouse Monoclonal anti-Reticulon 3 antibody has been validated for ELISA and IHC. It is suitable to detect Reticulon 3 in samples from Human.

Quick Overview for Reticulon 3 antibody (ABIN932228)

Target: Reticulon 3 (RTN3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Reticulon 3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Clone: 10A8

Product Details anti-Reticulon 3 Antibody

Immunogen: RTN3 antibody was raised in Mouse using a purified recombinant fragment of RTN3 expressed in E. coli as the immunogen.

Isotype: IgG2a

Application Details

Application Notes: ELISA: 1:10,000, IHC: 1:200-1:1000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for Reticulon 3

Target: Reticulon 3 (RTN3)

Alternative Name: RTN3

Background: RTN3 may be involved in membrane trafficking in the early secretory pathway. It is thought to inhibit BACE1 activity and amyloid precursor protein processing. It may induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. Synonyms: Monoclonal RTN3 antibody, Anti-RTN3 antibody, Reticulon 3 antibody.