TWIST1 antibody

Catalog No. ABIN933111

This anti-TWIST1 antibody is a Mouse Monoclonal antibody detecting TWIST1 in WB, ICC, FACS and DB. Suitable for Human.

Quick Overview for TWIST1 antibody (ABIN933111)

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TWIST1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Flow Cytometry (FACS), Dot Blot (DB)

Clone: Twist2C1a

Product Details anti-TWIST1 Antibody

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: TWIST antibody was raised in mouse using recombinant Human Twist Homolog 1 (Acrocephalosyndactyly 3, Saethre-Chotzen Syndrome) (Drosophila) (Twist1)

Isotype: IgG1

Application Details

Application Notes: WB: 0.2-2 µg/mL, FC: 0.5-2 µg/sample, ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: TWIST antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for TWIST1

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Alternative Name: TWIST

Background: Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue, in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome. Synonyms: Monoclonal TWIST antibody, Anti-TWIST antibody, Twist related protein 1 antibody, SCS antibody, ACS3 antibody, BPES2 antibody, BPES3 antibody, TWIST1 antibody.

Pathways: p53 Signaling, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity