ZW10 antibody

Catalog No. ABIN933128

The Mouse Monoclonal anti-ZW10 antibody is suitable to detect ZW10 in samples from Human. It has been validated for WB, ICC, IP and DB.

Quick Overview for ZW10 antibody (ABIN933128)

Target: ZW10 (Zw10 Kinetochore Protein (ZW10))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZW10 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Dot Blot (DB)

Clone: 3363C4a

Product Details anti-ZW10 Antibody

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: ZW10 antibody was raised in mouse using recombinant Human Zw10, Kinetochore Associated, Homolog (Drosophila) (Zw10)

Isotype: IgG1

Application Details

Application Notes: WB: 0.2-2 µg/mL, IP: 100-500 µg/sample, ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: ZW10 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for ZW10

Target: ZW10 (Zw10 Kinetochore Protein (ZW10))

Alternative Name: ZW10

Background: The interaction with Sm proteins inhibits their assembly on U RNA and interferes with snRNP biogenesis. Inhibits the binding of survival motor neuron protein (SMN) to Sm proteins. May participate in cellular volume control by activation of a swelling-induced chloride conductance pathway. Synonyms: Monoclonal ZW10 antibody, Anti-ZW10 antibody, HZW10 antibody, KNTC1AP antibody, MGC149821 antibody.