CD3 epsilon antibody (PE)

Catalog No. ABIN933429

The PE-conjugated Hamster Monoclonal anti-CD3 epsilon antibody (Clone 500-A2) (ABIN933429) specifically detects CD3 epsilon in FACS. The antibody is reactive with Mouse samples.

Quick Overview for CD3 epsilon antibody (PE) (ABIN933429)

Target: CD3 epsilon (CD3E)

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This CD3 epsilon antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: 500-A2

Product Details anti-CD3 epsilon Antibody (PE)

Immunogen: CD3 e antibody (PE) was raised in hamster using H-3 b-specific mouse cytotoxic T lymphocyte as the immunogen.

Isotype: IgG

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in PBS, with NaN3 added as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Product is photosensitive and should be protected from light.
Dilute only prior to immediate use.

Storage: 4 °C

Target Details for CD3 epsilon

Target: CD3 epsilon (CD3E)

Alternative Name: CD3e

Background: CD3e molecule, epsilon also known as CD3E is a polypeptide which in humans is encoded by the CD3E gene which resides on chromosome 11. The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Synonyms: Monoclonal CD3e antibody, Anti-CD3e antibody.

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway