TRAIL antibody

Catalog No. ABIN933806

The Mouse Monoclonal anti-TRAIL antibody has been validated for WB, ELISA and Inhibition. It is suitable to detect TRAIL in samples from Human.

Quick Overview for TRAIL antibody (ABIN933806)

Target: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TRAIL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Clone: M912292

Product Details anti-TRAIL Antibody

Immunogen: TRAIL antibody was raised in mouse using highly pure recombinant human TRAIL/APO-II as the immunogen.

Isotype: IgG1 kappa

Application Details

Application Notes: ELISA: 2-4 µg/mL, Inhibition: 0.3-0.6 µg/mL, WB: 0.25-0.5 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for TRAIL

Target: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Alternative Name: TRAIL

Background: TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic “death domain”, which activates the cell’s apoptotic machinery. Synonyms: Monoclonal TRAIL antibody, Anti-TRAIL antibody, TNF-related apoptosis-inducing Ligand antibody, TNFSF10 antibody, TL2 antibody.

Molecular Weight: 20.0 kDa (predicted detection band MW)

Pathways: Apoptosis, Positive Regulation of Endopeptidase Activity