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GATA3 antibody

This anti-GATA3 antibody is a Rat Monoclonal antibody detecting GATA3 in WB and IF. Suitable for Mouse.
Catalog No. ABIN933858

Quick Overview for GATA3 antibody (ABIN933858)

Target

See all GATA3 Antibodies
GATA3 (GATA Binding Protein 3 (GATA3))

Reactivity

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Mouse

Host

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Rat

Clonality

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Monoclonal

Conjugate

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This GATA3 antibody is un-conjugated

Application

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Western Blotting (WB), Immunofluorescence (IF)

Clone

KT77
  • Purification

    Protein G affinity chromatography

    Immunogen

    GATA3 antibody was raised in Rat using Mouse GATA-3 as the immunogen.

    Isotype

    IgG2a
  • Application Notes

    IF: 1-10 µg/mL, WB: 0.1-1 µg/mL
    Optimal conditions should be determined by the investigator.

    Restrictions

    For Research Use only
  • Concentration

    Lot specific

    Buffer

    Supplied in PBS containing 0.1 % sodium azide as a preservative

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    Storage

    -20 °C/-80 °C

    Storage Comment

    Store at 4 °C for up to 1 month. For long term storage, aliquot and store at -20 to -80 °C.
  • Target

    GATA3 (GATA Binding Protein 3 (GATA3))

    Alternative Name

    GATA3

    Background

    GATA3 belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T cell development and plays an important role in endothelial cell biology. GATA-3 has been shown to promote the secretion of IL-4, IL-5, and IL-13 from Th2 cells. GATA-3 was shown to be required for the luminal A type of breast cancer, intertwined in pathways with ER alpha. However, it is also hypothesised that GATA-3 may play tissue specific roles. Synonyms: Monoclonal GATA3 antibody, Anti-GATA3 antibody, GATA 3 antibody, GATA-3 antibody, Trans-acting T-cell specific transcription factor antibody.

    Pathways

    Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
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