SMC3 antibody

Catalog No. ABIN933863

The Rat Monoclonal anti-SMC3 antibody is suitable to detect SMC3 in samples from Mouse. It has been validated for WB.

Quick Overview for SMC3 antibody (ABIN933863)

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This SMC3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: KT75

Product Details anti-SMC3 Antibody

Purification: Protein G affinity chromatography

Immunogen: SMC3 antibody was raised in Rat using Mouse SMC3 and GST fusion protein as the immunogen.

Isotype: IgG2a

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Supplied in PBS containing 0.1 % sodium azide as a preservative

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C/-80 °C

Storage Comment: Store at 4 °C for up to 1 month. For long term storage, aliquot and store at -20 to -80 °C.

Target Details for SMC3

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Alternative Name: SMC3

Background: The SMC3 protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. Synonyms: Monoclonal SMC3 antibody, Anti-SMC3 antibody, SMC 3 antibody, SMC-3 antibody, Structural maintenance of chromosomes 3 antibody.

Pathways: Stem Cell Maintenance