Delangin-B antibody

Catalog No. ABIN933981

The Rat Monoclonal anti-Delangin-B antibody (Clone KT55) (ABIN933981) specifically detects Delangin-B in IF and WB. The antibody is reactive with Mouse samples.

Quick Overview for Delangin-B antibody (ABIN933981)

Target: Delangin-B

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Application: Immunofluorescence (IF), Western Blotting (WB)

Clone: KT55

Product Details

Purification: Protein A affinity chromatography

Immunogen: Delangin B antibody was raised in Rat using Delangin peptide coupled carrier protein as the immunogen.

Isotype: IgG2b

Application Details

Application Notes: IF: 10 µg/mL, WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Supplied in PBS containing 0.1 % sodium azide as a preservative

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C/-80 °C

Storage Comment: Store at 4 °C for up to 1 month. For long term storage, aliquot and store at -20 to -80 °C.

Target Details

Target: Delangin-B

Background: Delangin proteins facilitate enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Synonyms: Monoclonal Delangin B antibody, Anti-Delangin B antibody, Delangin-B antibody, NIPBL antibody, Delangin isoform B antibody.