Desmoglein 1 antibody

Catalog No. ABIN934355

Product Details anti-Desmoglein 1 Antibody

Target: Desmoglein 1 (DSG1)

Reactivity: Mammalian

Host: Mouse

Clonality: Monoclonal

Conjugate: This Desmoglein 1 antibody is un-conjugated

Application: Please inquire

Clone: Dsg1-P23

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied in liquid form

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for Desmoglein 1

Target: Desmoglein 1 (DSG1)

Alternative Name: DSG1 (DSG1 Products)

Background: Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, four desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus. Synonyms: Monoclonal Desmoglein 1 antibody, Anti Desmoglein 1 antibody, DSG1 antibody, CDHF4 antibody, DG1 antibody, Desmosomal glycoprotein 1 antibody, Cadherin family member 4 antibody, PPKS1 antibody, SPPK1 antibody.

Pathways: Cell-Cell Junction Organization