Optimal conditions should be determined byt he investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
Lot specific
Buffer
Supplied in liquid form
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 2-8 °C for short term storage. Aliquot and store at -20 °C for long term storage.
Target
Desmoglein 1 (DSG1)
Alternative Name
DSG1
Background
Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, four desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus. Synonyms: Monoclonal Desmoglein 1 antibody, Anti Desmoglein 1 antibody, DSG1 antibody, CDHF4 antibody, DG1 antibody, Desmosomal glycoprotein 1 antibody, Cadherin family member 4 antibody, PPKS1 antibody, SPPK1 antibody.