CEA
Reactivity: Human
WB, IHC, IP, ICC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal conditions should be determined byt he investigator.
Restrictions
For Research Use only
Concentration
Lot specific
Buffer
10 mM TRIS, pH 7.5, with 0.15 M NaCl, and 0.05 % NaN3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
Yang, Zeng: "Microfluidic communicating vessel chip for expedited and automated immunomagnetic assays." in: Lab on a chip, Vol. 18, Issue 24, pp. 3830-3839, (2019) (PubMed).
Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells. Synonyms: Monoclonal CEA antibody (biotin), Anti-CEA antibody (biotin), Carcinoembryonic Antigen antibody (biotin).