HSD17B3 antibody (Middle Region)

Catalog No. ABIN950183

The Rabbit Polyclonal anti-HSD17B3 antibody has been validated for WB, FACS, IHC (p) and EIA. It is suitable to detect HSD17B3 in samples from Human.

Quick Overview for HSD17B3 antibody (Middle Region) (ABIN950183)

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-HSD17B3 Antibody

Binding Specificity: AA 96-126, Middle Region

Specificity: This antibody recognizes Human 17-beta-HSD3 / HSD17B3 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 96~126 amino acids from the Central region of human 17-beta-HSD3 / HSD17B3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HSD17B3

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Alternative Name: 17-beta-HSD3 / HSD17B3

Background: This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.Synonyms: 17-beta-hydroxysteroid dehydrogenase type 3, EDH17B3, Testicular 17-beta-hydroxysteroid dehydrogenase, Testosterone 17-beta-dehydrogenase 3

Molecular Weight: 34516 Da

Gene ID: 3293

NCBI Accession: NP_000188

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis