HSD17B4 antibody (Middle Region)

Catalog No. ABIN950184

The Rabbit Polyclonal anti-HSD17B4 antibody (ABIN950184) specifically detects HSD17B4 in WB, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for HSD17B4 antibody (Middle Region) (ABIN950184)

Target: HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-HSD17B4 Antibody

Binding Specificity: AA 340-370, Middle Region

Specificity: This antibody recognizes Human 17-beta-HSD4 / HSD17B4 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 340-370 amino acids from the Central region of human 17-beta-HSD4 / HSD17B4

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HSD17B4

Target: HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Alternative Name: 17-beta-HSD4 / HSD17B4

Background: The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. [provided by RefSeq].Synonyms: 17-beta-hydroxysteroid dehydrogenase 4, D-bifunctional protein, DBP, EDH17B4, MFE-2, MFE2, Peroxisomal multifunctional enzyme type 2, SDR8C1

Molecular Weight: 79686 Da

Gene ID: 3295

NCBI Accession: NP_000405

Pathways: Monocarboxylic Acid Catabolic Process