ALX4 antibody (Middle Region)

Catalog No. ABIN950384

The Rabbit Polyclonal anti-ALX4 antibody has been validated for WB and EIA. It is suitable to detect ALX4 in samples from Human.

Quick Overview for ALX4 antibody (Middle Region) (ABIN950384)

Target: ALX4 (ALX Homeobox 4 (ALX4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALX4 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-ALX4 Antibody

Binding Specificity: AA 256-283, Middle Region

Specificity: This antibody reacts to ALX4.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 256-283 amino acids from the Central region of human ALX4

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ALX4

Target: ALX4 (ALX Homeobox 4 (ALX4))

Alternative Name: ALX4

Background: This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2), an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism, suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS), a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart.Synonyms: Homeobox protein aristaless-like 4, KIAA1788

Gene ID: 60529

NCBI Accession: NP_068745