AMH antibody (Middle Region)

Catalog No. ABIN950438

The Rabbit Polyclonal anti-AMH antibody has been validated for WB and IHC (p). It is suitable to detect AMH in samples from Human and Mouse. There is 1 publication available.

Quick Overview for AMH antibody (Middle Region) (ABIN950438)

Target: AMH (Anti-Mullerian Hormone (AMH))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-AMH Antibody

Binding Specificity: AA 430-460, Middle Region

Specificity: This antibody reacts to Anti-Muellerian Hormone.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 430~460 amino acids from the Central region of human AMH

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-AMH antibody (ABIN950438)

Segal, Kent, Wesche, Ng, Serra, Oulès, Kar, Emerton, Blackford, Darmanis, Miquel, Luong, Yamamoto, Bonham, Jassem, Heaton, Vigilante, King, Sancho, Teichmann, Quake, Nakauchi, Rashid: "Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors." in: Nature communications, Vol. 10, Issue 1, pp. 3350, (2019) (PubMed).

Target Details for AMH

Target: AMH (Anti-Mullerian Hormone (AMH))

Alternative Name: Anti-Muellerian Hormone / AMH

Background: Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.Synonyms: MIF, MIS, Muellerian-inhibiting factor, Muellerian-inhibiting substance

Gene ID: 268

NCBI Accession: NP_000470

Pathways: Negative Regulation of Hormone Secretion