ARHGAP10 antibody (Middle Region)

Catalog No. ABIN950486

The Rabbit Polyclonal anti-ARHGAP10 antibody is suitable to detect ARHGAP10 in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for ARHGAP10 antibody (Middle Region) (ABIN950486)

Target: ARHGAP10 (rho GTPase Activating Protein 10 (ARHGAP10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGAP10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-ARHGAP10 Antibody

Binding Specificity: AA 240-267, Middle Region

Specificity: This antibody reacts to ARHGAP10.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 240-267 amino acids from the Central region of human ARHGAP10

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ARHGAP10

Target: ARHGAP10 (rho GTPase Activating Protein 10 (ARHGAP10))

Alternative Name: ARHGAP10 / GRAF2

Background: GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).Synonyms: GTPase regulator associated with focal adhesion kinase 2, Graf-related protein 2, Rho GTPase-activating protein 10, Rho-type GTPase-activating protein 10

Gene ID: 79658

NCBI Accession: NP_078881