ARHGAP10 antibody (AA 237-263)

Catalog No. ABIN654652

This Rabbit Polyclonal antibody specifically detects ARHGAP10 in WB, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for ARHGAP10 antibody (AA 237-263) (ABIN654652)

Target: ARHGAP10 (rho GTPase Activating Protein 10 (ARHGAP10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGAP10 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB24573

Product Details anti-ARHGAP10 Antibody

Binding Specificity: AA 237-263

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ARHGAP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-263 amino acids from the Central region of human ARHGAP10.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ARHGAP10

Target: ARHGAP10 (rho GTPase Activating Protein 10 (ARHGAP10))

Alternative Name: ARHGAP10

Background: GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).

Molecular Weight: 89375

Gene ID: 79658

NCBI Accession: NP_078881

UniProt: A1A4S6