DCLRE1C antibody (N-Term)

Catalog No. ABIN950523

Product Details anti-DCLRE1C Antibody

Target: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Binding Specificity: AA 28-58, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCLRE1C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human Artemis (N-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 28~58 amino acids from the N-terminal region of Human DCLRE1C. Genename: DCLRE1C

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DCLRE1C

Target: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Alternative Name: Artemis (DCLRE1C Products)

Background: DCLRE1C is a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide.Synonyms: A-SCID protein, ASCID, DCLRE1C, DNA cross-link repair 1C protein, SCIDA, SNM1-like protein, SNM1C

Molecular Weight: 78436 Da

Gene ID: 64421

NCBI Accession: NP_001029027

Pathways: DNA Damage Repair