Ataxin 3 antibody (Middle Region)

Catalog No. ABIN950546

The Rabbit Polyclonal anti-Ataxin 3 antibody has been validated for WB, IHC (p), FACS and EIA. It is suitable to detect Ataxin 3 in samples from Human.

Quick Overview for Ataxin 3 antibody (Middle Region) (ABIN950546)

Target: Ataxin 3 (ATXN3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ataxin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Product Details anti-Ataxin 3 Antibody

Binding Specificity: AA 267-297, Middle Region

Specificity: This antibody reacts to Ataxin-3.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 267~297 amino acids from the Center region of human ATXN3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Ataxin 3

Target: Ataxin 3 (ATXN3)

Alternative Name: Ataxin-3

Background: ATXN3 was known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers.Synonyms: ATX3, ATXN3, MJD, MJD1, Machado-Joseph disease protein 1, SCA3, Spinocerebellar ataxia type 3 protein

Gene ID: 4287

NCBI Accession: NP_001121168