B3GALT5 antibody (N-Term)

Catalog No. ABIN950586

The Rabbit Polyclonal anti-B3GALT5 antibody (ABIN950586) specifically detects B3GALT5 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for B3GALT5 antibody (N-Term) (ABIN950586)

Target: B3GALT5 (UDP-Gal:betaGlcNAc beta 1,3-Galactosyltransferase, Polypeptide 5 (B3GALT5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This B3GALT5 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-B3GALT5 Antibody

Binding Specificity: AA 64-91, N-Term

Specificity: This antibody reacts to B3GALT5.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 64-91 amino acids from the N-terminal region of human B3GALT5

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for B3GALT5

Target: B3GALT5 (UDP-Gal:betaGlcNAc beta 1,3-Galactosyltransferase, Polypeptide 5 (B3GALT5))

Alternative Name: B3GALT5

Background: This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene encodes the most probable candidate for synthesis of the type 1 Lewis antigens which are frequently found to be elevated in gastrointestinal and pancreatic cancers. The encoded protein is inactive with N-linked glycoproteins and functions in mucin glycosylation. Five transcript variants have been described which differ in the 5' UTR. All transcript variants encode an identical protein.Synonyms: 3-GalTase 5, 3-galactosyltransferase 5, Beta-1, Beta-1, Beta-3-Gx-T5, Beta3Gal-T5, UDP-Gal:beta-GlcNAc beta-1, UDP-galactose:beta-N-acetylglucosamine beta-1, b3Gal-T5

Gene ID: 10317

NCBI Accession: NP_006048