BSDC1 antibody (C-Term)

Catalog No. ABIN950682

This anti-BSDC1 antibody is a Rabbit Polyclonal antibody detecting BSDC1 in WB, EIA. Suitable for Human.

Quick Overview for BSDC1 antibody (C-Term) (ABIN950682)

Target: BSDC1 (BSD Domain Containing 1 (BSDC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BSDC1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-BSDC1 Antibody

Binding Specificity: AA 396-425, C-Term

Specificity: This antibody reacts to BSDC1.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 396-425 amino acids from the C-terminal region of human BSDC1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for BSDC1

Target: BSDC1 (BSD Domain Containing 1 (BSDC1))

Alternative Name: BSDC1

Background: BSDC1 is a 430 amino acid protein encoded by a gene mapping to chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.Synonyms: BSD domain-containing protein 1

Gene ID: 55108

NCBI Accession: NP_060515