RCAN1 antibody (N-Term)

Catalog No. ABIN951003

This anti-RCAN1 antibody is a Rabbit Polyclonal antibody detecting RCAN1 in WB and EIA. Suitable for Human.

Quick Overview for RCAN1 antibody (N-Term) (ABIN951003)

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RCAN1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-RCAN1 Antibody

Binding Specificity: AA 40-68, N-Term

Specificity: This antibody recognizes Human RCAN1 (N-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 40-68 amino acids from the N-terminal region of Human RCAN1. Genename: RCAN1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RCAN1

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Alternative Name: Calcipressin-1

Background: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this geneSynonyms: ADAPT78, CSP1, DSC1, DSCR1, Down syndrome critical region protein 1, Myocyte-enriched calcineurin-interacting protein 1, RCAN1, Regulator of calcineurin 1

Molecular Weight: 28079 Da

Gene ID: 1827

NCBI Accession: NP_004405

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development