CBX8 antibody (Middle Region)

Catalog No. ABIN951075

This anti-CBX8 antibody is a Rabbit Polyclonal antibody detecting CBX8 in WB and EIA. Suitable for Human and Mouse.

Quick Overview for CBX8 antibody (Middle Region) (ABIN951075)

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX8 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-CBX8 Antibody

Binding Specificity: AA 160-189, Middle Region

Specificity: This antibody reacts to CBX8.

Cross-Reactivity (Details): Species reactivity (tested):Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 160-189 amino acids from the Central region of human CBX8

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CBX8

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Alternative Name: CBX8

Background: Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.Synonyms: Chromobox protein homolog 8, PC3, Polycomb 3 homolog, RC1, Rectachrome 1

Molecular Weight: 43396 Da

Gene ID: 57332

NCBI Accession: NP_065700