CBY1
Reactivity: Human
Host: Rabbit
Polyclonal
FITC
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
CBY1/PGEA1 (CBY1)
(Chibby Homolog 1 (CBY1))
Alternative Name
CBY1
Background
Inhibits the Wnt/Wingless pathway by binding to beta catenin and inhibiting beta catenin mediated transcriptional activation by competing with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin 2/PKD2 and possibly of other intracellular proteins.Synonyms: ARB1, ARPP-binding protein, C22orf2, CBY, Cytosolic leucine-rich protein, Golgi and endoplasmic reticulum-associated 1, HRIHFB2025, PGEA1, PIGEA-14, PKD2 interactor, Protein chibby homolog 1