ICOSLG antibody (C-Term)

Catalog No. ABIN951266

The Rabbit Polyclonal anti-ICOSLG antibody has been validated for WB and EIA. It is suitable to detect ICOSLG in samples from Human.

Quick Overview for ICOSLG antibody (C-Term) (ABIN951266)

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICOSLG antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-ICOSLG Antibody

Binding Specificity: AA 216-246, C-Term

Specificity: This antibody recognizes Human CD275 / ICOS Ligand (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 216-246 amino acids from the C-terminal region of human CD275 / ICOS Ligand

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ICOSLG

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Alternative Name: CD275 / ICOS Ligand

Background: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion, induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).Synonyms: B7 homolog 2, B7-like protein Gl50, B7-related protein 1, B7H2, B7RP-1, B7RP1, ICOSL, ICOSLG, KIAA0653

Molecular Weight: 33349 Da

Gene ID: 23308

NCBI Accession: NP_056074

Pathways: Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation