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CD55 antibody (PE)

CD55 Reactivity: Human, Primate FACS Host: Mouse Monoclonal MEM-118 PE

Catalog No. ABIN951352

Datasheet as PDF

Target See all CD55 Antibodies

CD55 (Complement Decay-Accelerating Factor (CD55))
Reactivity
105

32

7

4

4

4

3

2

2

2
Human, Primate
Host
69

62

6

5

3

1

1
Mouse
Compatible Secondaries
Clonality
84

61

2
Monoclonal
Conjugate
75

15

13

10

4

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD55 antibody is conjugated to PE
Application
90

77

42

33

28

25

17

15

14

14

8

4

4

3

1

1

1

1
Flow Cytometry (FACS)

Specificity

This antibody recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells, it is weakly present on NK cells.

Cross-Reactivity (Details)

Species reactivity (tested):Human, Non-Human Primates

Clone

MEM-118

Isotype

IgM

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anti-Complement Decay-Accelerating Factor (CD55) antibody
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Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Buffer

Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Target

CD55 (Complement Decay-Accelerating Factor (CD55))

Alternative Name

CD55 / DAF (CD55 Products)

Background

CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.Synonyms: Complement decay-accelerating factor

Gene ID

1604

Pathways

Complement System, Regulation of Leukocyte Mediated Immunity