ACTR1A antibody (Middle Region)

Catalog No. ABIN951473

The Rabbit Polyclonal anti-ACTR1A antibody is suitable to detect ACTR1A in samples from Human and Mouse. It has been validated for WB and EIA.

Quick Overview for ACTR1A antibody (Middle Region) (ABIN951473)

Target: ACTR1A (Alpha Centractin (ACTR1A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACTR1A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-ACTR1A Antibody

Binding Specificity: AA 97-126, Middle Region

Specificity: This antibody reacts to Centractin alpha.

Cross-Reactivity (Details): Species reactivity (tested):Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of human ACTR1A

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ACTR1A

Target: ACTR1A (Alpha Centractin (ACTR1A))

Alternative Name: Centractin alpha

Background: This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin.Synonyms: ACTR1A, ARP1, Actin-RPV, CTRN1, Centrosome-associated actin homolog

Gene ID: 10121

NCBI Accession: NP_005727

Pathways: M Phase