CHADL antibody (Middle Region)

Catalog No. ABIN951491

The Rabbit Polyclonal anti-CHADL antibody is suitable to detect CHADL in samples from Human. It has been validated for WB and EIA.

Quick Overview for CHADL antibody (Middle Region) (ABIN951491)

Target: CHADL (Chondroadherin-Like (CHADL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHADL antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-CHADL Antibody

Binding Specificity: AA 405-434, Middle Region

Specificity: This antibody reacts to CHADL.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 405-434 amino acids from the Central region of human CHADL

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CHADL

Target: CHADL (Chondroadherin-Like (CHADL))

Alternative Name: CHADL

Background: Members of the small leucine-rich proteoglycan (SLRP) family are mostly extracellular proteins that function upstream of multiple signaling cascades. They affect intracellular phosphorylation and modulate distinct pathways, such as those driven by Toll-like receptors, TGF? and receptor tyrosine kinases. As a member of the SLRP family, CHADL (Chondroadherin-like protein) is a 762 amino acid protein containing 21 LRR (leucine-rich) repeats, which promote protein-ligand interactions. Chondroadherin, a closely related protein, promotes attachment of chrondocytes, osteoblasts and fibroblasts and also plays an important role in the regulation of chrodrocyte proliferation and growth. CHADL is a secreted protein that is located in the extracellular space. There are two isoforms of CHADL that exist as a result of alternative splicing events.Synonyms: Chondroadherin-like protein, SLRR4B

Molecular Weight: Isoform2 74kd. 82388 Da

Gene ID: 150356

NCBI Accession: NP_612490