Claudin 22 (CLDN22) (AA 97-126), (Middle Region) antibody
Quick Overview for Claudin 22 (CLDN22) (AA 97-126), (Middle Region) antibody (ABIN951558)
Target
See all Claudin 22 (CLDN22) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 97-126, Middle Region
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Specificity
- This antibody recognizes CLDN22 (Center).
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Cross-Reactivity (Details)
- Species reactivity (tested):Human and Mouse.
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Purification
- Protein A column, followed by peptide affinity purification
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Immunogen
- KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of human CLDN22
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % (W/V) Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Claudin 22 (CLDN22)
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Alternative Name
- CLDN22
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Background
- This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3' UTR of the WWC2 gene (GeneID: 80014) on the opposite strand.Synonyms: Claudin-22
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Molecular Weight
- 24509 Da
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Gene ID
- 53842
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NCBI Accession
- NP_001104789
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Pathways
- Cell-Cell Junction Organization, Hepatitis C
Target
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