Claudin 22 (CLDN22) (AA 90-117) antibody

Catalog No. ABIN5538726

Product Details

Target: Claudin 22 (CLDN22)

Binding Specificity: AA 90-117

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CLDN22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-117 amino acids from the Central region of human CLDN22.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.43 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details

Target: Claudin 22 (CLDN22)

Alternative Name: CLDN22 (CLDN22 Products)

Synonyms: CLDN21 antibody, 2210404A22Rik antibody, 5330431C14Rik antibody, 9530051B05Rik antibody, CLDN22 antibody, claudin 22 antibody, claudin-22 antibody, CLDN22 antibody, Cldn22 antibody, LOC102186369 antibody

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3' UTR of the WWC2 gene (GeneID: 80014) on the opposite strand.

Molecular Weight: 25 kDa

Gene ID: 53842

UniProt: Q8N7P3

Pathways: Cell-Cell Junction Organization, Hepatitis C