Coilin antibody (Middle Region)

Catalog No. ABIN951619

This Rabbit Polyclonal antibody specifically detects Coilin in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for Coilin antibody (Middle Region) (ABIN951619)

Target: Coilin (COIL)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Coilin antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Coilin Antibody

Binding Specificity: AA 156-186, Middle Region

Specificity: This antibody reacts to COIL.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 156-186 amino acids from the Central region of human COIL

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Coilin

Target: Coilin (COIL)

Alternative Name: Coilin

Background: The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.Synonyms: CLN80, COIL, p80

Molecular Weight: 62608 Da

Gene ID: 8161

NCBI Accession: NP_004636

Pathways: Ribonucleoprotein Complex Subunit Organization