L2HGDH antibody (Middle Region)

Catalog No. ABIN951995

The Rabbit Polyclonal anti-L2HGDH antibody has been validated for WB and EIA. It is suitable to detect L2HGDH in samples from Human and Mouse.

Quick Overview for L2HGDH antibody (Middle Region) (ABIN951995)

Target: L2HGDH (L-2-Hydroxyglutarate Dehydrogenase (L2HGDH))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This L2HGDH antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-L2HGDH Antibody

Binding Specificity: AA 139-167, Middle Region

Specificity: This antibody detects L2HGDH/ Duranin.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse

Purification: Purified through a protein A column; followed by peptide affinity purification.

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 139-167aa) of human L2HGDH/Duranin.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for L2HGDH

Target: L2HGDH (L-2-Hydroxyglutarate Dehydrogenase (L2HGDH))

Alternative Name: Duranin

Background: The L2HGDH gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.Synonyms: C14orf160, L-2-hydroxyglutarate dehydrogenase, L2HGDH, hydroxyglutarate dehydrogenase

Gene ID: 79944

NCBI Accession: NP_079160