Emilin1 antibody

Catalog No. ABIN952077

This anti-Emilin1 antibody is a Rat Monoclonal antibody detecting Emilin1 in WB, IHC (fro) and IF. Suitable for Mouse.

Quick Overview for Emilin1 antibody (ABIN952077)

Target: Emilin1 (EMILIN1) (Elastin Microfibril Interfacer 1 (EMILIN1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Emilin1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Clone: C11A8

Product Details anti-Emilin1 Antibody

Specificity: This antibody was selected for its ability to detect Murine Emilin-1.

Cross-Reactivity (Details): Species reactivity (tested):Mouse.

Purification: Affinity Chromatography on Protein G

Immunogen: Recombinant Mouse Emilin-1

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in sterile water to a concentration is 0.1-1.0 mg/mL. Centrifuge vial prior to opening.

Buffer: PBS

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C for one month or at -20 °C for longer. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Emilin1

Target: Emilin1 (EMILIN1) (Elastin Microfibril Interfacer 1 (EMILIN1))

Alternative Name: EMILIN1

Background: Emilin-1 is an extracellular matrix glycoprotein localized at sites where elastin and microfibrils are in proximity. It may be responsible for anchoring smooth muscle cells to elastic fibers. It has cell adhesive capacity. Emilin-1 may have a role in the regulation of blood vessel assembly since it inhibits TGFB signaling by binding specifically to the pro-TGFB precursor and preventing its maturation by furin convertases in the extracellular space. TGFB proteins are the main regulators of blood vessel development and maintenance.Synonyms: EMI, EMILIN-1, Elastin microfibril interface-located protein 1, Elastin microfibril interfacer 1

Gene ID: 100952

NCBI Accession: NP_598679

UniProt: Q99K41