EXT1 antibody (Middle Region)
Quick Overview for EXT1 antibody (Middle Region) (ABIN952144)
Target
See all EXT1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 297-326, Middle Region
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Specificity
- This antibody recognizes Human EXT1 (Center).
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Purification
- Affinity Chromatography on Protein A
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Immunogen
- KLH conjugated synthetic peptide between 297-326 amino acids from the Central region of Human EXT1
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- EXT1 (Exostosin 1 (EXT1))
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Alternative Name
- Exostosin-1
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Background
- This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses. [provided by RefSeq].Synonyms: EXT1, Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Multiple exostoses protein 1, Putative tumor suppressor protein EXT1
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Molecular Weight
- 86255 Da
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Gene ID
- 2131
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NCBI Accession
- NP_000118
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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