FASTK antibody (C-Term)

Catalog No. ABIN952267

This Rabbit Polyclonal antibody specifically detects FASTK in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for FASTK antibody (C-Term) (ABIN952267)

Target: FASTK (Fas-Activated serine/threonine Kinase (FASTK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FASTK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-FASTK Antibody

Binding Specificity: AA 394-424, C-Term

Specificity: This antibody recognizes Human FAST kinase (C-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 394-424 amino acids from the C-terminal region of human FASTK.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FASTK

Target: FASTK (Fas-Activated serine/threonine Kinase (FASTK))

Alternative Name: FAST Kinase

Background: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.Synonyms: FASTK, Fas-activated serine/threonine kinase

Molecular Weight: 61104 Da

Gene ID: 10922

NCBI Accession: NP_006703